m-PEG3-thiol
This product is a high-purity methoxy PEG derivative featuring a terminal thiol group and a methoxy group at opposite ends of a short PEG3 spacer, specifically providing solubility, flexibility, and a reactive handle for conjugation.
Key Features and Benefits
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Thiol Group – Reactive site for forming stable thioether bonds via maleimide, haloacetyl, or gold surface conjugation.
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Methoxy Group – Provides stability and reduces nonspecific interactions.
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PEG3 Spacer – Enhances solubility, flexibility, and reduces steric hindrance in bioconjugates.
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High Purity – Suitable for bioconjugation, surface modification, and drug delivery applications.
Applications
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Conjugation to maleimide-activated biomolecules and probes
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Surface immobilization on gold nanoparticles or electrodes
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PEGylation of proteins, peptides, or small molecules
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Development of antibody–drug conjugates and targeted delivery systems
Storage & Handling
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Storage: Store at –20 °C, dry, and protected from light.
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Use: Dissolve in anhydrous solvents (e.g., DMF, DMSO). Avoid repeated freeze–thaw cycles.
This product provides a thiol group for versatile conjugation and a methoxy end for stability, with a short PEG3 spacer that specifically improves solubility and reduces steric hindrance in bioconjugates and surface modifications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
