m-PEG3-S-Acetyl
This product is a heterobifunctional PEG reagent featuring a terminal S-acetyl-protected thiol and a methoxy cap on the opposite end. The PEG3 spacer provides hydrophilicity and flexibility, while the protected thiol allows controlled deprotection for selective conjugation in bioconjugation and material science.
Key Features and Benefits:
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S-Acetyl Protection: Provides stable, deprotectable thiol functionality.
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Methoxy Cap: Ensures a non-reactive terminus for defined orientation.
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PEG3 Spacer: Enhances solubility and steric flexibility.
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Orthogonal Reactivity: Supports stepwise, multifunctional synthesis.
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High Purity: Guarantees reproducibility in advanced workflows.
Applications:
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Bioconjugation: Couples biomolecules through controlled thiol release.
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Drug Delivery: Provides thiol handles for PEGylated scaffolds.
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Probe Development: Builds thiol-reactive intermediates for imaging tools.
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Material Science: Functionalizes surfaces and nanoparticles with cleavable thiols.
Storage and Handling:
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO); deprotect thiol under mild conditions.
This product integrates controlled thiol reactivity with a compact PEG3 spacer, specifically offering solubility and precision for advanced conjugation strategies.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.