HS-(CH2)6-O-PEG8-OCH3
This product is a heterobifunctional PEG linker containing a terminal thiol, an eight-unit PEG chain, and a methoxy-capped end. The thiol enables selective coupling to maleimides, gold surfaces, or disulfide exchange, while the methoxy group prevents undesired crosslinking. The PEG8 spacer enhances solubility, flexibility, and hydrophilicity, making this reagent especially useful in bioconjugation, surface modification, and nanotechnology.
Key Features and Benefits
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Thiol Group: Couples efficiently with maleimides, gold, or disulfide exchange.
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Methoxy End-Cap: Provides stability and prevents crosslinking.
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PEG8 Spacer: Improves solubility, hydrophilicity, and accessibility.
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Versatile Functionality: Suitable for biomolecule and material modification.
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High Purity: Produced to ≥95% purity for reproducibility.
Applications
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Bioconjugation: Links thiol-reactive biomolecules or probes.
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Surface Modification: Functionalizes gold, nanoparticles, or other surfaces.
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Nanotechnology: Stabilizes nanostructures with PEGylated thiol layers.
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Drug Delivery: Acts as a modular PEGylation linker in therapeutic systems.
Storage and Handling
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Storage: Store at –20 °C in a sealed, desiccated container.
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Handling: Use freshly prepared solutions; thiols are prone to oxidation.
This product combines thiol reactivity, PEG solubility, and methoxy stability in an especially versatile linker for advanced conjugation and nanotech applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
