HS-(CH2)6-O-PEG8-OCH3, is a bifunctional reagent used in bioconjugation and protein modification applications. The reagent consists of a thiol group, an eight-unit polyethylene glycol (PEG) chain, and a methoxy group connected by a six-unit hexylene chain.
The thiol group is a highly reactive group that can selectively react with maleimides, vinyl sulfones, or other electrophiles. The PEG chain acts as a hydrophilic spacer, improving the solubility and accessibility of the target molecule. The methoxy group acts as a blocking group, preventing unwanted reactions with other functional groups.
HS-(CH2)6-O-PEG8-OCH3 is commonly used to attach biomolecules such as proteins or peptides to surfaces, for example, in the production of biosensors or immobilization of enzymes. It can also be used to introduce a spacer between two biomolecules, improving their interactions or accessibility.
HS-(CH2)6-O-PEG8-OCH3 is a white to off-white powder that is soluble in a range of polar solvents, such as DMSO, DMF, or ethanol. It should be stored at -20°C in a dry and dark place to maintain its stability and quality.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
