HO-PEG4-t-butyl ester
This product is a high-purity PEG derivative featuring a terminal hydroxyl group and a tert-butyl ester, specifically linked by a PEG4 spacer for enhanced solubility and flexibility.
Key Features and Benefits
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Hydroxyl Group – Provides a reactive handle for further chemical modifications such as esterification, etherification, or coupling reactions.
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t-Butyl Ester Moiety – Acid-labile protecting group that can be selectively cleaved to generate a free carboxyl group.
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PEG4 Spacer – Improves aqueous solubility, reduces steric hindrance, and enhances molecular flexibility.
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High Purity – Suitable for advanced applications in bioconjugation, polymer research, and drug delivery.
Applications
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Precursor for functional PEG derivatives
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Scaffold for bioconjugation and surface modification
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Linker in drug delivery and diagnostic systems
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Intermediate in polymer–drug conjugates
Storage & Handling
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Storage: Store at –20 °C, dry, and protected from light.
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Use: Dissolve in anhydrous solvents (e.g., DCM, DMF, DMSO). Avoid repeated freeze–thaw cycles.
This product provides a hydroxyl group and a cleavable tert-butyl ester on a PEG4 spacer, offering solubility, flexibility, and a versatile platform for further chemical modification.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
