Folate-PEG4-Azide
This product is a heterobifunctional PEG4 linker with a folate group for receptor targeting and a terminal azide for click chemistry. The PEG4 spacer enhances solubility and flexibility, making this reagent especially valuable for targeted delivery, bioconjugation, and imaging applications.
Key Features and Benefits:
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Folate Group: Binds with high affinity to folate receptors, enabling targeted delivery.
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Azide Group: Compatible with CuAAC and SPAAC click chemistry with alkynes.
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PEG4 Spacer: Improves hydrophilicity and reduces steric hindrance.
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High Purity: Ensures reproducibility in therapeutic and diagnostic research.
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Targeted Reactivity: Combines receptor targeting with orthogonal conjugation.
Applications:
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Targeted Drug Delivery: Direct therapeutic payloads to folate receptor–positive cells.
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Bioconjugation: Attach folate to biomolecules or nanoparticles via click chemistry.
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Molecular Imaging: Label probes for receptor-specific imaging.
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Surface Modification: Functionalize polymers or nanomaterials with folate ligands.
Storage and Handling:
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Storage: Store at –20 °C in a dry, light-protected container.
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Handling: Use anhydrous solvents (e.g., DMSO, DMF) for maximum reactivity.
This product combines folate receptor targeting with click-chemistry reactivity, making it an especially versatile tool for drug delivery and imaging strategies.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
