Folate-NH-ethylamine
This product is a heterobifunctional derivative consisting of a folate moiety linked to an ethylamine group. The folate enables high-affinity targeting of folate receptor–expressing cells, while the terminal amine serves as a versatile handle for conjugation through amide bond formation with carboxyls or activated esters. This compact design makes it especially useful for targeted drug delivery, probe development, and bioconjugation.
Key Features and Benefits
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Folate Moiety: Targets folate receptor–positive cells with high affinity.
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Ethylamine Group: Couples efficiently with carboxyls or activated esters.
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Compact Structure: Minimizes steric hindrance while preserving targeting efficiency.
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Dual Utility: Combines receptor targeting with functional conjugation chemistry.
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High Purity: Produced to ≥95% purity for reproducibility.
Applications
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Targeted Drug Delivery: Directs therapeutic conjugates to folate receptor–expressing tumors.
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Antibody and Protein Conjugation: Couples folate to proteins for selective targeting.
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Probe Development: Builds folate-functionalized probes for imaging and diagnostics.
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Bioconjugation: Serves as a receptor-targeting intermediate in multifunctional linker systems.
Storage and Handling
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Dissolve freshly in dry solvent; avoid repeated freeze–thaw cycles.
This product integrates receptor-specific folate targeting with amine conjugation chemistry in a compact scaffold, specifically providing a powerful tool for therapeutic and diagnostic applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
