FmocNHPEG2-BocNH-Tyrosine Methyl Ester is a chemical reagent that is widely used in the field of peptide synthesis. It is a derivative of tyrosine, which is an amino acid that is frequently incorporated into peptides due to its aromatic properties and ability to participate in hydrogen bonding.
The reagent consists of a tyrosine residue that has been protected with a Boc (tert-butoxycarbonyl) group to prevent unwanted reactions from occurring during the synthesis process. Additionally, an Fmoc (fluorenylmethyloxycarbonyl) group has been added to the amino group of the tyrosine residue, which serves as a temporary protecting group that can be removed under appropriate conditions. The Fmoc group protects the amine from unwanted reactions during peptide synthesis and is removed to expose the free amine group for further chemical modification. A PEG (polyethylene glycol) linker has also been added to the Boc-protected tyrosine residue to increase its solubility in water and enhance its overall stability.
FmocNHPEG2-BocNH-Tyrosine Methyl Ester is often used as a building block in the synthesis of peptides and other biologically active molecules. It can be incorporated into a peptide chain through solid-phase synthesis or solution-phase synthesis methods, depending on the specific application. Once the peptide has been synthesized, the Fmoc and Boc protecting groups can be removed under appropriate conditions to expose the free amine and carboxylic acid groups, which can then be used for further chemical modification or bioconjugation.
FmocNHPEG2-BocNH-Tyrosine Methyl Ester is a versatile and useful reagent for the synthesis of peptides and related molecules. Its unique properties make it an attractive option for a variety of applications in both academic and industrial settings. The presence of the Fmoc and Boc protecting groups provides excellent control over the peptide synthesis process, and the PEG linker enhances its solubility and stability in water.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
