Fmoc-NH-PEG9-acid
Fmoc-NH-PEG9-acid is a PEG linker containing an Fmoc-protected amine, a PEG9 spacer, and a terminal carboxylic acid. It enables orthogonal amine deprotection and carboxyl conjugation, offering a soluble and flexible scaffold for bioconjugation and synthetic applications.
Key Features and Benefits
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Fmoc-Protected Amine: Allows selective deprotection for orthogonal reactivity.
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Carboxylic Acid: Couples efficiently with amines to form stable amide bonds.
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PEG9 Spacer: Provides solubility, flexibility, and moderate chain length.
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Dual Functionality: Combines protected amine chemistry with reactive acid functionality.
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High Purity: Ensures reproducibility in conjugation and synthesis workflows.
Applications
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Bioconjugation: Links PEG chains to biomolecules with orthogonal control.
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Probe Development: Builds multifunctional probes for diagnostics and imaging.
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Drug Delivery: Provides PEG scaffolds with flexible length and reactive handles.
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Organic Synthesis: Serves as a versatile intermediate for modular linker design.
Storage and Handling
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents such as DMF or DMSO to maintain stability.
This product integrates a protected amine with carboxyl functionality in a PEG9 scaffold, specifically providing a versatile tool for conjugation and synthesis.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
