Fmoc-NH-PEG19-acid
This product is a PEG linker containing an Fmoc-protected amine, a PEG19 spacer, and a terminal carboxylic acid. It enables orthogonal amine deprotection and carboxyl conjugation, specifically providing a long, flexible, and soluble scaffold for bioconjugation and synthesis.
Key Features and Benefits
-
Fmoc-Protected Amine: Allows controlled deprotection for orthogonal reactivity.
-
Carboxylic Acid: Couples efficiently with amines to form stable amide bonds.
-
PEG19 Spacer: Provides long-chain solubility, flexibility, and biocompatibility.
-
Dual Functionality: Combines protected amine chemistry with reactive acid functionality.
-
High Purity: Ensures reproducibility in sensitive conjugation workflows.
Applications
-
Bioconjugation: Links PEG chains to biomolecules with orthogonal control.
-
Probe Development: Builds multifunctional probes for diagnostics and imaging.
-
Drug Delivery: Provides PEGylated scaffolds with flexible length and dual reactivity.
-
Organic Synthesis: Serves as a versatile intermediate for modular linker design.
Storage and Handling
-
Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
-
Handling: Use anhydrous solvents such as DMF or DMSO to maintain stability.
This product integrates an Fmoc-protected amine with a reactive carboxyl group in a PEG19 scaffold, specifically offering versatile functionality for conjugation and synthesis.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
