Fmoc-NH-PEG10-acid
This product is a PEG linker containing an Fmoc-protected amine, a PEG10 spacer, and a terminal carboxylic acid. It enables orthogonal amine deprotection and amide coupling, specifically providing a soluble and flexible scaffold for bioconjugation and synthesis.
Key Features and Benefits
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Fmoc-Protected Amine: Allows selective deprotection for orthogonal reactivity.
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Carboxylic Acid: Couples efficiently with amines to form stable amide bonds.
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PEG10 Spacer: Provides solubility, flexibility, and medium chain length.
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Dual Functionality: Combines amine protection with reactive acid chemistry.
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High Purity: Ensures reproducibility in bioconjugation and synthesis workflows.
Applications
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Bioconjugation: Links PEG chains to biomolecules with orthogonal control.
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Probe Development: Builds multifunctional probes for diagnostics and imaging.
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Drug Delivery: Provides PEG scaffolds with flexible length and dual reactivity.
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Organic Synthesis: Serves as an intermediate for modular linker design.
Storage and Handling
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents such as DMF or DMSO to maintain stability.
This product integrates Fmoc-protected amine chemistry with carboxyl functionality in a PEG10 scaffold, specifically offering orthogonal and versatile conjugation.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
