Fmoc-NH-PEG-Mal, MW 8K has been extensively used in the development of protein and peptide-based drug delivery systems. The maleimide group can react with thiol-containing proteins or peptides, such as cysteine residues, to form site-specific conjugates with controlled stoichiometry and orientation. The resulting bioconjugates exhibit enhanced stability, prolonged circulation time, and improved pharmacokinetics and biodistribution profiles, leading to improved therapeutic efficacy and reduced side effects.
In addition to drug delivery systems, Fmoc-NH-PEG-Mal, MW 8K can also be used in the development of biosensors, imaging agents, and other biomedical applications. Its flexible PEG chain can be functionalized with various functional groups to introduce different properties and functions, while the maleimide group allows for the site-specific attachment of biomolecules onto surfaces or nanoparticles.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
