DM1-MCC-PEG3-Biotin (CAS 2183472-94-6) is a compound combining the cytotoxic agent , an MCC linker, a PEG3 spacer, and a biotin moiety. It enables targeted drug delivery and is widely used in antibody-drug conjugates (ADCs) and biochemical research.
Key Features:
- DM1: Microtubule inhibitor for cytotoxic activity.
- MCC Linker: Conjugates to thiol groups for targeted delivery.
- PEG3 Spacer: Improves solubility and reduces steric hindrance.
- Biotin: Binds strongly to avidin or streptavidin for targeting.
Applications:
- ADC Development: Delivers DM1 to cancer cells with high specificity.
- Targeted Drug Delivery: Utilizes biotin-avidin interactions for precise targeting.
- Biochemical Studies: Explores cell biology and drug delivery mechanisms.
DM1-PEG3-Biotin enhances therapeutic precision, reducing systemic toxicity in targeted treatments.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
