DBCO-S-S-acid CAS:2749426-25-1 is a type of chemical compound with a long-chain alkyl group and a thioester moiety attached to a carboxylic acid group. It is commonly used as a linker in various bioconjugation procedures.
High-purity DBCO-S-S-acid from Axispharm is a cleavable ADC linker that can be used in the synthesis of antibody-drug conjugates for the introduction of carboxylic acid moieties into azide-containing biomolecules using copper-free Click Chemistry. The disulfide bonds in this linker can be cleaved using reducing agents such as DTT, BME, and TCEP. PEG spacer arms provide better solubility of labeled molecules in aqueous media.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.