DBCO-PEG4-Val-Ala-PAB-PNP CAS:2348405-93-4 is a small molecule linker that contains several functional groups, including DBCO, PEG, a valine-alanine dipeptide, a p-aminobenzyloxycarbonyl (PAB) protecting group, and a p-nitrophenyl (PNP) leaving group.
The DBCO group is a highly reactive cyclooctyne functional group that can react with azide groups in a bioorthogonal manner, allowing for the selective labeling and conjugation of biomolecules. The PEG chain improves the solubility and biocompatibility of the linker, while the dipeptide and PAB groups can be used to target specific cells or tissues. The PNP leaving group can be cleaved under mild conditions to release the linker from the conjugated molecule.
DBCO-PEG4-Val-Ala-PAB-PNP is commonly used in the field of bioconjugation and drug delivery, as it can be used to selectively label and conjugate biomolecules, such as proteins, peptides, and nucleic acids. Its unique chemical properties and biocompatibility make it a valuable tool for targeted drug delivery and imaging in various diseases.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.