DBCO-PEG24-NHS ester CAS:2765066-38-2 is a DBCO NHS ester that contains two functional groups: an N-hydroxysuccinimide (NHS) ester group and a dibenzocyclooctyne (DBCO) group. The NHS ester group is known for its ability to react with primary amines, while the DBCO group can react with azide functional groups via the copper-catalyzed azide-alkyne cycloaddition (CuAAC) reaction.
DBCO-PEG24-NHS ester has been extensively utilized in the development of bioconjugation strategies for pharmaceutical research and development. Its unique chemical properties allow for the covalent attachment of biomolecules, such as peptides, proteins, and antibodies, to other molecules, such as drug molecules or surfaces of medical devices, through a variety of chemical reactions.
The DBCO-PEG24-NHS ester compound provides a versatile platform for the development of innovative drug delivery systems and biomedical devices. Its use can lead to enhanced drug efficacy and reduced toxicity, as well as improved biocompatibility of medical devices.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
