DBCO-PEG-Thiol, MW 5K has been used extensively in pharmaceutical research and development as a conjugation tool for drug delivery systems, imaging agents, and diagnostic tools. The molecule’s unique combination of functional groups allows for precise control over conjugation chemistry, resulting in highly specific and targeted products.
In drug delivery, DBCO-PEG-Thiol, MW 5K has been used to develop antibody-drug conjugates (ADCs), where a cytotoxic drug is conjugated to an antibody targeting a specific cancer cell marker. The resulting ADCs can selectively deliver the drug to cancer cells, reducing off-target toxicity and improving efficacy.
In imaging and diagnostics, DBCO-PEG-Thiol, MW 5K has been used to develop contrast agents for magnetic resonance imaging (MRI) and positron emission tomography (PET). By conjugating DBCO-PEG-Thiol to a specific targeting molecule, such as a peptide or antibody, the resulting contrast agent can selectively bind to the target of interest, improving imaging resolution and sensitivity.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.