DBCO-NH-PEG2-NHS ester CAS: 2666999-50-2 contains three important functional groups, including a dibenzylcyclooctyne (DBCO) group, an N-hydroxysuccinimide (NHS) ester, and a PEG linker.
The DBCO group is known for its ability to undergo bioorthogonal click chemistry with azide-functionalized molecules, making it a valuable tool for targeted drug delivery and imaging applications. The NHS ester is another important functional group that allows for the covalent attachment of biomolecules to surfaces, including proteins, peptides, and small molecules.
DBCO-NH-PEG2-NHS ester has been extensively utilized in the development of novel drug delivery systems and imaging probes. Its unique chemical properties allow for the covalent attachment of therapeutic agents, such as antibodies or peptides, to the PEG linker via NHS ester coupling, which can then be conjugated to DBCO-functionalized imaging agents or nanoparticles. The resulting conjugates exhibit improved stability, increased solubility, and enhanced targeting efficiency in vivo, leading to improved therapeutic efficacy and reduced side effects.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
