DBCO-Acid, Dibenzocyclooctyne-acid
CAS: 1353016-70-2
Description:
Dibenzocyclooctyne-acid is a reactive compound containing a dibenzocyclooctyne group and a carboxylic acid group. The DBCO group allows for copper-free click chemistry with azide-functionalized molecules, while the carboxylic acid group enables conjugation with amines through amide bond formation. This compound is widely used in bioconjugation applications, especially for the creation of stable bioconjugates in biomedical research.
Key Features:
- DBCO Group: Enables strain-promoted, copper-free click chemistry with azide groups, ideal for bioorthogonal reactions in complex biological systems.
- Carboxylic Acid Group: Allows for covalent attachment to amine-containing molecules through amide bond formation.
- Versatility: Ideal for use in drug delivery, protein labeling, and surface functionalization.
DBCO-Acid Applications:
- Bioconjugation: Used for linking biomolecules with azide-functionalized probes or therapeutic agents through bioorthogonal chemistry.
- Drug Delivery Systems: Facilitates stable conjugation of drugs to biomolecules for targeted delivery.
- Protein and Antibody Labeling: Suitable for modifying proteins and antibodies for imaging and therapeutic studies.
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