β-D-Tetraacetylgalactopyranoside-PEG3-azide
β-D-Tetraacetylgalactopyranoside-PEG3-azide is a high-purity heterobifunctional PEG linker with a β-D-tetraacetylgalactopyranoside for glycan-mediated targeting and an azide for copper-catalyzed (CuAAC) or strain-promoted (SPAAC) click chemistry. The PEG3 spacer specifically improves solubility, flexibility, and reduces steric hindrance, enabling efficient conjugation in aqueous and organic systems. This reagent is especially ideal for glycoconjugate synthesis, bioorthogonal labeling, and targeted delivery applications.
Key Features and Benefits
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β-D-Tetraacetylgalactopyranoside Moiety: Facilitates glycan-based recognition and targeting.
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Azide Group: Compatible with CuAAC and SPAAC click reactions.
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PEG3 Spacer: Enhances solubility and accessibility of reactive groups.
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Heterobifunctional Design: Supports orthogonal and site-specific conjugations.
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High Purity: Supplied at >95% purity for reliable results.
Applications
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Glycoprotein and glycoconjugate synthesis.
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Targeted drug delivery via glycan recognition.
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Bioorthogonal labeling in glycobiology research.
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Nanoparticle and surface functionalization with carbohydrate ligands.
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Development of glycan-based probes and diagnostics.
Storage and Handling
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Storage: Store at –20 °C, dry, and protected from light.
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Handling: Use anhydrous solvents such as DMF or DMSO; avoid moisture to preserve reactivity and acetyl protection.
This product combines glycan-targeting capability with versatile azide click chemistry, linked by a PEG3 spacer specifically for optimal solubility and flexibility in glycobiology and targeted delivery.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
