Cbz-N-Amido-PEG24-acid
This product is a long-chain PEG24 linker with a Cbz-protected amide and a terminal carboxylic acid. The PEG24 spacer provides excellent hydrophilicity and flexibility, while the Cbz group offers stable carbamate protection for controlled, stepwise conjugation.
Key Features and Benefits:
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Cbz-Protected Amide: Stable protecting group for selective deprotection.
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Carboxylic Acid Group: Couples efficiently with amines to form amide bonds.
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PEG24 Spacer: Provides long-chain solubility, flexibility, and low steric hindrance.
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High Purity: Ensures reproducible results in synthetic and bioconjugation workflows.
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Orthogonal Chemistry: Supports multistep synthesis strategies.
Applications:
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Bioconjugation: Link proteins, peptides, or small molecules with precise spacing.
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Drug Delivery: Long PEG spacer enhances solubility and pharmacokinetics.
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Surface Modification: Functionalize nanoparticles, hydrogels, or biomaterials.
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Material Science: Integrate into PEGylated polymers and advanced materials.
Storage and Handling:
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Storage: Store at –20 °C, protected from moisture and light.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to maintain stability.
This product combines a long PEG chain with Cbz protection and carboxyl functionality, making it an especially powerful reagent for orthogonal synthesis and advanced conjugation strategies.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
