Bz-rC Phosphoramidite (CAS 118380-84-0), also known as N4-Bz-5′-O-DMTr-2′-O-(N3-Tfa) aminopropyl cytidine 3′-CED phosphoramidite, is a TBDMS-protected phosphoramidite monomer used in the synthesis of DNA and RNA oligonucleotides. It is a benzoyl-protected cytidine derivative, designed to protect the amine group of cytidine during oligonucleotide assembly.
Key Features:
- CAS Number: 118380-84-0
- Chemical Structure: N4-Benzoyl-5′-O-DMTr-2′-O-(N3-Tfa) aminopropyl cytidine 3′-CED phosphoramidite
- Function: Building block for creating RNA and DNA oligonucleotides
- Protection Groups: TBDMS-protected phosphoramidite, which allows selective reactivity during synthesis
- Application: Used in solid-phase synthesis of RNA or DNA sequences for research and therapeutic purposes
This phosphoramidite is essential for precise oligonucleotide synthesis, enabling the construction of modified nucleotides for applications in gene editing, diagnostics, and therapeutic research.
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