BS2G Crosslinker
This product is a water-soluble, homobifunctional NHS ester crosslinker. It contains two sulfo-NHS ester groups connected by a glutarate spacer, enabling efficient and stable amide bond formation with primary amines. BS2G is non-cleavable, highly soluble in aqueous buffers, and especially used for protein-protein, protein-peptide, and biomolecule conjugations.
Key Features and Benefits:
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Homobifunctional Crosslinker: Contains two NHS ester groups for amine-to-amine conjugation.
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Water-Soluble: Eliminates the need for organic solvents.
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Non-Cleavable Linkage: Provides stable, permanent crosslinks.
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Glutarate Spacer: Ensures defined spacing and reduced steric hindrance.
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High Efficiency: Rapid, reproducible reactions under mild aqueous conditions.
Applications:
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Protein-Protein Crosslinking: Stabilize protein complexes for biochemical studies.
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Peptide Conjugation: Attach peptides or small amines to carrier proteins.
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Bioconjugate Development: Ideal for immunology, enzyme studies, and labeling assays.
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Surface Modification: Functionalize biomaterials or nanoparticles with amine-reactive chemistry.
Storage and Handling:
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Storage: Store desiccated at –20 °C, away from light and moisture.
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Handling: Prepare fresh solutions before use; hydrolyzes in aqueous buffer.
This product offers strong, stable amine-to-amine conjugation in aqueous systems, making it an especially versatile tool for protein research and bioconjugation.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
