Bromoacetamido-PEG4-NHS ester
This product is a heterobifunctional linker featuring a bromoacetamide group for selective thiol conjugation and an NHS ester for amine coupling. The PEG4 spacer enhances solubility and spacing, making it especially useful in bioconjugation, probe development, and drug delivery.
Key Features and Benefits:
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Bromoacetamide Group: Reacts selectively with thiols to form stable thioether bonds.
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NHS Ester: Couples rapidly with primary amines under mild conditions.
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PEG4 Spacer: Provides solubility, hydrophilicity, and reduced steric hindrance.
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Dual Reactivity: Supports orthogonal thiol- and amine-targeted conjugation.
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High Purity: Ensures reproducibility in sensitive workflows.
Applications:
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Bioconjugation: Links thiol- and amine-containing biomolecules.
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Probe Development: Builds multifunctional probes for imaging and diagnostics.
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Drug Delivery: Supports PEGylated linkers for targeted therapeutic conjugates.
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Material Science: Functionalizes polymers, nanoparticles, and biomaterials.
Storage and Handling:
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Storage: Store at –20 °C in a sealed, moisture- and light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO); avoid exposure to strong nucleophiles.
This product integrates thiol- and amine-reactive groups in a PEG4 scaffold, specifically offering solubility and versatility for advanced conjugation strategies.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
