Bis-sulfone-PEG3-azide (CAS: 1802908-01-5)
Features:
- Functional Groups: Contains bis-sulfone and azide groups, enabling versatile chemical reactions and disulfide bridge formation.
- PEG3 Spacer: Incorporates a triethylene glycol linker for enhanced solubility and flexibility.
- Molecular Weight: Approximately 700.82 g/mol.
- Purity: Typically ≥95%.
- Physical Form: Supplied as a colorless to light yellow liquid.
Applications:
- Antibody-Drug Conjugates (ADCs): Functions as a cleavable linker in ADC synthesis, facilitating targeted drug delivery.
- Click Chemistry: The azide group supports azide-alkyne cycloaddition reactions, including copper-catalyzed and strain-promoted processes.
- Bioconjugation: Enables biomolecule attachment via the PEG3 spacer, improving solubility and reducing steric hindrance.
- Proteomics Research: Used in labeling and crosslinking studies to explore protein interactions and functions.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
