Bis-PEG13-t-butyl ester CAS:2225903-65-9 is a bifunctional, hydrophilic polyethylene glycol (PEG) linker with t-butyl ester groups on both ends. Its unique structure imparts exceptional stability, solubility, and biocompatibility, making it an ideal component for various pharmaceutical research and development applications.
Introduction to the Application:
In pharmaceutical R&D, Bis-PEG13-t-butyl ester serves as a versatile linker for constructing prodrugs, antibody-drug conjugates (ADCs), and other bioconjugates. The bifunctional nature of the linker enables the attachment of two bioactive molecules, enhancing therapeutic efficacy and reducing side effects. Additionally, its hydrophilic properties can improve drug solubility and pharmacokinetics, while the t-butyl ester groups facilitate controlled release, optimizing drug delivery and performance.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
