Bis-PEG11-t-butyl ester is a bifunctional PEGylation reagent with t-butyl ester functional groups at both ends. It exhibits enhanced hydrophilicity and biocompatibility, making it an essential tool in the modification of biomolecules, such as proteins and peptides, for pharmaceutical applications.
Introduction to the application in pharmaceutical research and development:
In pharmaceutical R&D, Bis-PEG11-t-butyl ester plays a pivotal role in the PEGylation of bioactive molecules, improving their solubility, stability, and pharmacokinetic properties. Its utilization enhances drug delivery, reduces immunogenicity, and extends the circulation time of therapeutic agents, thus significantly contributing to the development of more efficacious and safer medications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.