Biotin-PEG36-acid
This product is a long-chain PEG linker featuring a biotin moiety for high-affinity avidin/streptavidin binding and a terminal carboxylic acid for amide coupling. The PEG36 spacer provides excellent solubility, extended flexibility, and low steric hindrance, making it especially ideal for bioconjugation, drug delivery, and probe development.
Key Features and Benefits:
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Biotin Moiety: Enables strong and specific binding to avidin/streptavidin systems.
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Carboxylic Acid: Couples efficiently with primary amines via amide bond formation.
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PEG36 Spacer: Provides long, flexible spacing and exceptional solubility.
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High Affinity + Functionality: Combines biotin binding with conjugation chemistry.
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High Purity: Ensures reproducibility for research and development workflows.
Applications:
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Bioconjugation: Links biomolecules via biotin–avidin interaction and amide chemistry.
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Drug Delivery: Builds long-chain PEGylated scaffolds with reduced aggregation.
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Probe Development: Creates biotin-functionalized probes for imaging and diagnostics.
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Material Science: Functionalizes surfaces and nanoparticles with biotin handles.
Storage and Handling:
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to preserve reactivity.
This product combines strong biotin affinity with carboxyl reactivity in an extended PEG36 scaffold, specifically offering solubility, spacing, and multifunctionality for advanced applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
