Biotin-PEG3-NH-Mal
This product is a heterobifunctional linker with a biotin moiety for avidin/streptavidin binding and a maleimide for thiol conjugation. The PEG3 spacer improves solubility, flexibility, and biotin accessibility, making it especially ideal for affinity labeling and multifunctional bioconjugation.
Key Features and Benefits:
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Biotin Group: Provides strong, specific binding to avidin/streptavidin systems.
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Maleimide Group: Selectively reacts with thiols to form stable thioether linkages.
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PEG3 Spacer: Enhances hydrophilicity and reduces steric hindrance.
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Dual Reactivity: Combines affinity capture with thiol-selective conjugation.
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High Purity: Ensures reproducibility in labeling and conjugation workflows.
Applications:
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Affinity Labeling: Biotinylation of proteins, peptides, or antibodies for pull-down assays.
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Bioconjugation: Links thiol-containing biomolecules with streptavidin systems.
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Drug Delivery: PEGylated scaffold improves solubility and stability.
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Probe Development: Builds multifunctional probes for imaging and diagnostic tools.
Storage and Handling:
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Storage: Store at –20 °C in a tightly sealed, light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to maintain maleimide stability.
This product provides both biotin affinity and thiol reactivity in a compact PEG3 framework, making it an especially versatile reagent for bioconjugation and targeted labeling.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
