Biotin-PEG2-NH-Mal
This bifunctional PEG2 linker carries biotin, an amine, and a maleimide group. Biotin enables high-affinity binding to avidin/streptavidin, while the maleimide reacts selectively with thiols for targeted bioconjugation and labeling.
Key Features and Benefits:
-
Biotin Moiety: Provides strong, specific binding to streptavidin or avidin.
-
Maleimide Group: Selective thiol-reactivity for cysteine-containing biomolecules.
-
PEG2 Spacer: Enhances solubility and reduces steric hindrance.
-
Amine Handle: Versatile site for additional coupling or derivatization.
-
High Purity: Ensures reliable performance in sensitive labeling workflows.
Applications:
-
Affinity Labeling: Biotinylation of proteins, peptides, or antibodies for detection.
-
Bioconjugation: Dual-reactive linker for thiol and amine crosslinking.
-
Surface Modification: Functionalize nanoparticles or biosensors with biotin handles.
-
Drug Delivery: Incorporate biotin tags for targeted or affinity-based delivery systems.
Storage and Handling:
-
Storage: Store at –20 °C, protected from moisture and light.
-
Handling: Use anhydrous solvents (e.g., DMSO, DMF) to maintain amine and maleimide reactivity.
This product combines biotin affinity with maleimide thiol reactivity and an amine handle, making it an especially versatile linker for affinity assays, protein conjugation, and surface functionalization.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
