Biotin-PEG2-Azide
This product is a heterobifunctional PEG linker containing a biotin moiety, a PEG2 spacer, and a terminal azide group. It specifically enables streptavidin binding and copper-catalyzed or copper-free click chemistry, offering solubility and versatile dual reactivity.
Key Features and Benefits
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Biotin Moiety: Provides strong affinity for streptavidin and avidin systems.
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Azide Group: Reacts with alkynes via CuAAC or SPAAC click chemistry.
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PEG2 Spacer: Enhances solubility while maintaining compact length.
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Dual Reactivity: Combines biotin affinity capture with azide click chemistry.
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High Purity: Ensures reproducibility in labeling and conjugation workflows.
Applications
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Bioconjugation: Links biomolecules with streptavidin and alkyne-modified partners.
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Probe Development: Builds multifunctional probes for imaging and diagnostics.
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Drug Delivery: Provides PEG scaffolds with affinity and click handles.
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Material Science: Functionalizes nanoparticles and surfaces with biotin and azide groups.
Storage and Handling
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents such as DMSO or DMF; avoid prolonged moisture exposure.
This product integrates biotin affinity with azide click chemistry in a PEG2 scaffold, specifically offering compact, soluble, and multifunctional conjugation capability.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
