Biotin-PEG2-Azide (CAS: 1910803-72-3) is a PEG derivative featuring a biotin group and an azide group. It efficiently reacts with alkynes, DBCO, and BCN through Click Chemistry, forming stable triazole linkages. The PEG2 spacer boosts solubility, minimizes steric hindrance, and provides flexibility, enhancing binding to streptavidin and avidin.
Key Features:
- Click Chemistry Ready: Quickly reacts with alkynes and cyclooctyne derivatives for stable linkage.
- Improves Solubility: The PEG2 spacer increases water solubility of biotin-conjugated molecules.
- Enhanced Binding: Reduces steric hindrance for better biotin-streptavidin/avidin interaction.
Applications: Ideal for biotinylating DNA, proteins, and other biomolecules for labeling, detection, and purification in research and diagnostics.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
