Biotin-PEG11-Azide (CAS: 2276672-04-7, 956494-20-5) is a highly versatile compound used in chemical research, bioconjugation, and click chemistry. It contains a biotin group, an 11-unit polyethylene glycol (PEG) spacer, and an azide group. These features work together to enhance biomolecule conjugation and functionalization. As a result, it’s perfect for applications in drug discovery, diagnostics, and nanotechnology.
Key Features:
- Biotin Group: The biotin group forms strong, specific interactions with avidin or streptavidin. Therefore, it’s ideal for targeted delivery and detection in biochemical assays.
- PEG11 Spacer: The PEG11 spacer improves solubility, flexibility, and biocompatibility. This, in turn, boosts performance in both aqueous and biological environments.
- Azide Group: The azide group enables efficient click chemistry. It makes conjugation with alkyne-functionalized molecules easy, resulting in stable and controlled linkages.
- Water Solubility: Biotin-PEG11-Azide dissolves easily in water and polar solvents. Thus, it offers flexibility for various experimental setups.
- High Purity: The compound ensures reliable, consistent results. This makes it ideal for both research and industrial applications.
Applications:
- Click Chemistry: Biotin-PEG11-Azide is perfect for conjugating biomolecules, small molecules, and peptides. As a result, it plays a key role in drug discovery, diagnostics, and nanomedicine.
- Bioconjugation: It efficiently links peptides, proteins, and nucleic acids. This makes it an excellent choice for therapeutic and diagnostic applications.
- Targeted Drug Delivery: Thanks to its biotin-avidin binding properties, it’s great for targeted drug delivery and cellular imaging. This ensures precise molecular targeting.
- Nanotechnology: It is widely used to functionalize nanoparticles. Thus, it enhances drug delivery, imaging, and diagnostic capabilities.
- Protein Labeling: It plays a critical role in protein labeling and detection assays. This is particularly useful for research involving biotin-binding proteins like avidin or streptavidin.
Conclusion:
In conclusion, Biotin-PEG11-Azide (CAS: 2276672-04-7, 956494-20-5) is a vital tool for modern chemical research. With its biotin group, PEG11 spacer, and azide group, it’s perfect for click chemistry, bioconjugation, and targeted drug delivery. Moreover, its high solubility, purity, and flexibility make it ideal for a wide range of research and industrial applications.
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