Biotin-PEG11-amine
This product is a heterobifunctional PEG11 linker containing a biotin moiety for avidin/streptavidin binding and a terminal primary amine for amide coupling. The PEG11 spacer specifically provides excellent hydrophilicity, flexibility, and extended spacing, ensuring high biotin accessibility in bioconjugation and labeling applications.
Key Features and Benefits:
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Biotin Group: Enables high-affinity binding to avidin and streptavidin systems.
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Amine Group: Couples efficiently with carboxyls, NHS esters, and other electrophiles.
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PEG11 Spacer: Enhances solubility, reduces steric hindrance, and improves biotin accessibility.
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High Purity: Ensures reproducibility in sensitive conjugation workflows.
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Dual Functionality: Combines affinity labeling with versatile amine reactivity.
Applications:
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Affinity Labeling: Biotinylation of proteins, peptides, and antibodies.
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Bioconjugation: Facilitates multifunctional linker strategies for dual labeling.
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Drug Delivery: PEGylated design improves solubility and targeting efficiency.
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Surface Functionalization: Functionalizes nanoparticles, hydrogels, and biosensor platforms.
Storage and Handling:
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Storage: Store at –20 °C in a sealed, light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to maintain amine stability.
This product combines biotin’s strong binding with amine-based conjugation in a long PEG spacer, making it an especially versatile tool for bioconjugation, drug delivery, and affinity capture.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
