BCN-carbamate-PEG2-Bromide

BCN-carbamate-PEG2-Bromide CAS:2243150-62-9 is a chemical compound that consists of a polyethylene glycol (PEG) chain with a BCN (trans-cyclooctene) functional group, a carbamate linker, and a bromide functional group attached to one end. BCN is a strained cyclic alkene that can undergo a rapid and highly selective reaction with tetrazines to form a stable covalent bond, making it a valuable tool for bioconjugation applications.

BCN-carbamate-PEG2-Bromide is used as a linker molecule for the modification of peptides and proteins. The bromide functional group can be used to facilitate the attachment of the BCN-carbamate-PEG2-Bromide to a target molecule through nucleophilic substitution reactions. The BCN functional group can then be used to react with tetrazine-functionalized molecules to form a stable covalent bond between the two molecules.

BCN-carbamate-PEG2-Bromide is often used in the development of drug delivery systems, where it can be used to modify drug molecules, peptides, or proteins to increase their solubility, stability, and bioavailability. It can also be used to prepare bioconjugates for diagnostic and therapeutic applications. The PEG chain in BCN-carbamate-PEG2-Bromide can impart hydrophilicity and biocompatibility, making it a useful tool in the design of biomaterials.

AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.