Azido-PEG6-NHS ester CAS:2055014-64-5 linker contains an azide group and an NHS ester. The PEG spacer increases the aqueous solubility of the resulting compound. The azide group readily reacts with alkyne, BCN, DBCO through Click Chemistry to yield a stable triazole linkage. The NHS ester is widely used to label the primary amines (-NH2) of biomolecules such as proteins, oligonucleotides, and etc.
Azido-PEG6-NHS ester has also been employed in the development of site-specific labeling strategies, which enable the attachment of fluorophores or other reporter molecules to specific amino acid residues of a protein or peptide. This enables the study of protein-protein interactions, enzyme kinetics, and other biological processes.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
