Azido-PEG24-NHS ester CAS:2375600-46-5 contains an azido functional group (-N3) attached to the end of a PEG chain, which is activated by an N-hydroxysuccinimide (NHS) ester group. The azido group is known for its ability to react with other molecules through click chemistry.
Azido-PEG24-NHS ester has been extensively utilized in the development of novel drug conjugates and bioconjugation reactions. Its unique chemical properties allow for the covalent attachment of therapeutic agents, such as antibodies and peptides, to the PEG chain via click chemistry reactions. The resulting conjugates exhibit improved stability, increased solubility, and prolonged circulation time in vivo, leading to enhanced therapeutic efficacy and reduced side effects.
In addition to its use in drug conjugation, Azido-PEG24-NHS ester has also been employed as a surface modifier in various biomedical applications. For example, it can be immobilized onto the surface of medical devices or implants to improve biocompatibility and reduce immune response.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
