Azido-PEG12-NHS CAS:2363756-50-5 estercontains an azide functional group (-N3) attached to the end of a PEG chain via an NHS ester linker. The azide group is known for its ability to undergo click chemistry reactions.
Azido-PEG12-NHS ester has been extensively used in the development of drug delivery systems and biomaterials. Its unique chemical properties allow for the covalent attachment of biomolecules, such as proteins, peptides, and antibodies, to the PEG chain via click chemistry reactions. The resulting conjugates exhibit improved stability, enhanced biocompatibility, and prolonged circulation time in vivo, leading to improved therapeutic efficacy and reduced side effects.
Azido-PEG12-NHS ester has also been employed in the development of bioconjugation strategies for targeted drug delivery and diagnostic imaging. The azide group can be selectively functionalized with various targeting ligands, such as antibodies or peptides, allowing for specific targeting of diseased tissues or cells.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
