APDye 594 TCO reacts with a tetrazine to produce a stable covalent bond, also known as an anti-electron-demanding Diels-Alder cycloaddition. The reaction is extremely fast (k > 800 M-1 s-1), selective, biocompatible, and does not require copper catalysts or high temperatures. This excellent reaction rate constant is unmatched by any other bioorthogonal reaction pair described to date.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.