Amino-PEG8-acid
This product is a high-purity heterobifunctional PEG linker featuring a terminal primary amine and a terminal carboxylic acid group, separated by a PEG8 spacer specifically to improve solubility and flexibility.
Key Features and Benefits
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Primary Amine Group – Provides a reactive handle for coupling with carboxyls, NHS esters, or other electrophiles.
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Carboxylic Acid Group – Enables amide bond formation with amines for bioconjugation.
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PEG8 Spacer – Enhances aqueous solubility, reduces steric hindrance, and increases conformational flexibility.
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High Purity – Suitable for protein modification, probe design, and drug delivery research.
Applications
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Crosslinking proteins, peptides, or antibodies
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Amide coupling for probe, polymer, and nanoparticle functionalization
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Linker for drug delivery systems and targeted therapeutics
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Surface modification in biosensors and biomaterials
Storage & Handling
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Storage: Store at –20 °C, dry, and protected from light.
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Handling: Dissolve in anhydrous solvents (e.g., DMF, DMSO) or aqueous buffers when appropriate. Avoid repeated freeze–thaw cycles.
This product combines a reactive amine and carboxyl group on a PEG8 spacer, providing a versatile and soluble linker specifically for bioconjugation, crosslinking, and surface functionalization.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
