Amino-PEG4-tris-PEG4-alkyne contains two functional groups, an amino group (-NH2) and an alkyne group (-C≡CH) separated by a PEG chain. A tris-PEG4 linker is used to connect the amino and alkyne groups, providing a stable and flexible bridge between the two.
The amino group is known for its ability to react with other molecules through amide bond formation, while the alkyne group can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions, also known as click chemistry. This unique combination of functional groups makes Amino-PEG4-tris-PEG4-alkyne a useful tool in the field of pharmaceutical research and development.
Amino-PEG4-tris-PEG4-alkyne has been widely used in the development of bioconjugation strategies for the delivery of therapeutic agents. The amino group can be used to conjugate a variety of molecules, such as peptides, antibodies, and small molecules, to the PEG chain via amide bond formation. Meanwhile, the alkyne group can be used to react with azide-functionalized molecules using CuAAC reactions, allowing for the efficient attachment of a wide range of payloads.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
