Amino-PEG12-acid
This product is a bifunctional PEG12 linker with a terminal amine and a carboxylic acid. The PEG12 spacer provides extended hydrophilicity, flexibility, and moderate spacing, making it especially suitable for bioconjugation, drug delivery, and surface modification.
Key Features and Benefits:
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Amine Group: Couples efficiently with carboxyls, NHS esters, and other electrophiles.
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Carboxylic Acid Group: Reacts with amines to form stable amide bonds.
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PEG12 Spacer: Offers solubility, flexibility, and reduced steric hindrance.
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High Purity: Ensures reproducibility in sensitive workflows.
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Dual Reactivity: Supports orthogonal and multistep conjugation strategies.
Applications:
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Bioconjugation: Link proteins, peptides, and biomolecules with controlled PEG spacing.
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Drug Delivery: PEGylated linker enhances solubility and pharmacokinetics.
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Surface Functionalization: Functionalizes nanoparticles, hydrogels, or polymers.
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Material Science: Integrates into PEGylated scaffolds for advanced systems.
Storage and Handling:
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Storage: Store at –20 °C in a dry, light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to maintain reactivity.
This product provides a balance of chain length and dual-reactive functionality, making it an especially versatile reagent for advanced conjugation and drug delivery applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
