Amine-PEG-amine (NH2-PEG-NH2), MW 3.5K
Amine-PEG-amine (NH2-PEG-NH2), MW 3.5K is a versatile reagent used in biochemical research, pharmaceutical development, and formulation applications. This compound features a polyethylene glycol (PEG) chain with amine groups at both ends, making it ideal for various conjugation, modification, and formulation processes.
Key Features
- Bifunctional Amine Groups: Two amine groups enable stable covalent bonding with other molecules.
- PEG Chain: Enhances solubility and stability of the attached biomolecules.
- Molecular Weight: 3.5 kDa, providing a balanced size for effective modifications.
Applications
- Bioconjugation: Attaches to proteins, peptides, and antibodies, improving their stability and solubility.
- Drug Development: PEGylates therapeutic agents to enhance pharmacokinetics and reduce immunogenicity.
- Chemical Synthesis: Acts as a linking agent in various chemical reactions.
- Formulation: Used in the development of drug formulations to improve the solubility, stability, and bioavailability of active pharmaceutical ingredients (APIs).
Advantages
- Improved Solubility: The PEG component increases the solubility of conjugated molecules and APIs.
- Stable Linkage: Terminal amine groups ensure robust and stable conjugation.
- Enhanced Biocompatibility: Reduces immunogenicity and improves compatibility with biological systems.
- Optimized Formulations: Enhances the performance of pharmaceutical formulations by improving drug delivery and stability.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
