Acid-PEG5-t-butyl ester CAS:1309460-29-4 is a chemical compound used in organic synthesis and bioconjugation reactions. It is a derivative of polyethylene glycol (PEG) that contains a t-butyl ester group at one end and a carboxylic acid group at the other end, connected by a PEG spacer consisting of five ethylene glycol units.
The presence of the carboxylic acid group allows for specific and efficient labeling of the Acid-PEG5-t-butyl ester with amines or other nucleophiles through amide bond formation. The t-butyl ester group can be removed under acidic conditions, exposing the carboxylic acid group and enabling further chemical reactions.
Acid-PEG5-t-butyl ester is often used in the synthesis of various bioconjugates, such as drug conjugates, protein conjugates, and surface coatings, due to its water solubility, biocompatibility, and ease of modification. It can be used to modify the physicochemical properties of biomolecules, enhance their stability, or improve their pharmacokinetic profile.
Acid-PEG5-t-butyl ester is a useful tool in bioconjugation chemistry and drug delivery, as it enables specific and efficient modification of biomolecules and their properties, which can lead to the development of new and improved therapeutics.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
