5-Methyl-2′-Fluoro-U Phosphoramidite, CAS 182700-06-7, plays a crucial role in biomedicine. It serves as a key building block in the synthesis of modified nucleic acids, with 5-methyl and 2′-fluoro modifications that boost stability, binding, and resistance to enzymatic degradation. This compound drives progress in antisense oligonucleotide development, targeting specific genes or RNA sequences. It helps combat a variety of health issues, including viral infections and genetic disorders.
Key Features
- 5-Methyl and 2′-Fluoro Modifications: Increase stability, binding strength, and nuclease resistance in oligonucleotides.
- Phosphoramidite Chemistry: Integrates easily with standard DNA/RNA synthesis, ensuring smooth incorporation.
- Targeted Gene Interaction: Enables selective targeting of genes or RNA for therapeutic purposes.
Applications
- Antisense Oligonucleotides: Enhances treatments for genetic disorders and viral infections, boosting stability and effectiveness.
- siRNA Therapeutics: Improves the pharmacokinetics of RNA-based drugs, making them more potent and long-lasting.
- Nucleic Acid Research: Supports studies on gene regulation, nucleic acid interactions, and molecular structures.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
