4-(4-(4-(3-fluorobenzyloxy)-3-chlorophenylamino)quinazolin-6-yl)phenol, a derivative of the quinazoline-containing drug lapatinib. Lapatinib reversibly blocks the phosphorylation of epidermal growth factor receptor (EGFR), ErbB2, Erk-1 and -2, and AKT kinases; it acts to inhibit cells in human tumor cell lines and xenografts Cyclin D protein levels.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
