3-Azidopropylamine (CAS: 88192-19-2) is a bifunctional compound with an azide (-N₃) and an amine (-NH₂) group. Its dual reactivity makes it ideal for bioconjugation, click chemistry, and molecular synthesis.
Key Features:
- Molecular Formula: C₃H₈N₄
- Molecular Weight: 100.12 g/mol
- Physical State: Colorless to light yellow liquid
- Solubility: Soluble in water, DMSO, DMF, dichloromethane, THF, and chloroform
3-Azidopropylamine Applications:
- Bioconjugation:
- The amine group reacts with activated esters (e.g., NHS esters), enabling the introduction of azide functionalities into biomolecules.
- Click Chemistry:
- The azide group participates in CuAAC reactions, enabling molecular conjugation with alkyne-containing compounds.
Handling and Storage:
- Storage: Store at -20°C under inert gas; stable for 24 months.
- Sensitivity: Air and heat sensitive; handle in an inert atmosphere.
- Safety: Flammable liquid; causes skin and eye irritation. Use protective gear and ensure proper ventilation.
3-Azidopropylamine is commonly used in synthetic chemistry, molecular labeling, and bioconjugation applications due to its reactivity and versatility.
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