3-(Acetylthio)propionic acid N-succinimidyl ester CAS:84271-78-3 is a small molecule compound that is commonly used as a crosslinking agent in bioconjugation applications. It is composed of several functional groups, including an acetylthio group, a propionic acid group, and a succinimidyl ester group.
The acetylthio group is a functional group that contains a sulfur atom and is commonly used as a protecting group for reactive thiol groups. The propionic acid group is a carboxylic acid group that contains a three-carbon chain, which can be used to link the molecule to other compounds. The succinimidyl ester group is a functional group that contains a nitrogen atom and is commonly used as a reactive group for bioconjugation applications.
When used in bioconjugation applications, 3-(Acetylthio)propionic acid N-succinimidyl ester can be used to crosslink different molecules together, such as proteins or DNA strands. The succinimidyl ester group can react with amine groups on one molecule, while the acetylthio group can react with thiol groups on another molecule, creating a stable crosslinked product. This type of crosslinking can be used to create novel biomaterials, such as hydrogels or scaffolds, or to create functionalized surfaces for biosensors or medical devices.
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