1,1,1-Trifluoroethyl-PEG3-Propargyl CAS:1835759-73-3 is a chemical compound that is widely used in pharmaceutical research and development. It is composed of a trifluoroethyl group, a PEG (polyethylene glycol) chain, and a propargyl group. The trifluoroethyl group improves the compound’s solubility and metabolic stability, while the PEG chain improves its pharmacokinetics and biocompatibility. The propargyl group, on the other hand, enables the compound to react with other molecules that contain azide groups, forming stable triazole linkages.
In pharmaceutical research and development, 1,1,1-Trifluoroethyl-PEG3-Propargyl is used to modify drugs or other molecules, allowing for targeted delivery to specific cells or tissues. This modification can improve the pharmacokinetics and efficacy of drugs, while also reducing their toxicity and immunogenicity. Additionally, it can be used as a starting material for the synthesis of bioconjugates or prodrugs, which are biologically inactive compounds that can be converted into active drugs in the body. These unique chemical properties make 1,1,1-Trifluoroethyl-PEG3-Propargyl an essential tool in drug discovery and development, and a valuable component of modern pharmaceutical research.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
