1,1,1-Trifluoroethyl-PEG2-azide is a crosslinker containing an azide group and a trifluroethyl group. The azide group can participate in Click Chemistry reactions with reagents such as alkynes, DBCO and BCN. The PEG modification increases the aqueous solubility of the resulting compound. The trifluoroethyl group is thought to be an amide isotere and used to interact with lysine and other primary amine groups in proteins, antibody and other molecules and surfaces.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.