Fmoc-NH-PEG28-acid (CAS: 2101605-02-9), also known as Fmoc-NH-PEG28-CH₂CH₂COOH, is a PEG-based linker with an Fmoc-protected amine and a terminal carboxylic acid (COOH). The PEG28 spacer enhances water solubility and flexibility, making it ideal for peptide synthesis and bioconjugation. The Fmoc group allows controlled deprotection, while the carboxylic acid enables stable amide bond formation with amine groups.
Key Features:
- Fmoc-Protected Amine: Allows selective deprotection for further functionalization.
- PEG28 Spacer: Increases solubility and reduces steric interference.
- Terminal Carboxylic Acid: Suitable for conjugation with amine-containing biomolecules.
Applications:
- Peptide Synthesis: Acts as a useful building block for solid-phase peptide synthesis.
- Bioconjugation: Enables attachment of biomolecules in research and therapeutic applications.
- Drug Delivery Development: Assists in creating PEGylated compounds for improved pharmacokinetics.
Storage and Handling:
- Storage: Store at -20°C in a dry, dark environment.
- Handling: Use proper protective equipment and ventilation when handling.
Fmoc-NH-PEG28-COOH is a versatile linker for peptide synthesis and bioconjugation, enhancing solubility and functionalization options for various biochemical applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
