Methylcyclopropene-PEG3-Aldehyde (Methylcyclopropene-PEG3-CHO): Overview and Applications
Product Summary
Methylcyclopropene-PEG3-Aldehyde, is a specialized linker molecule used in bioconjugation. It features a methylcyclopropene group for bioorthogonal reactions and an aldehyde group (–CHO) that readily reacts with amines or hydrazines, allowing for stable linkage to various biomolecules. The PEG3 spacer enhances solubility and flexibility, making it ideal for applications requiring selective and efficient bonding.
Applications
- Antibody-Drug Conjugates (ADCs)
- Enables precise drug attachment to antibodies for targeted therapeutic delivery.
- Biomolecule Labeling
- Allows selective labeling of proteins, peptides, or nucleic acids through aldehyde-amine or aldehyde-hydrazine reactions.
- Surface Modification
- Suitable for attaching bioactive molecules to surfaces, enhancing biosensor and diagnostic tool performance.
- Targeted Drug Delivery
- Facilitates targeted conjugation in drug delivery systems, improving efficacy and reducing off-target effects.
- Click Chemistry Applications
- Supports bioorthogonal click reactions, enabling efficient, selective conjugations in complex environments.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
